Purpose and methods of a bidomain reaction-diffusion model of the
SIAM Conference on the Life Sciences minisimposium on cardiac modeling Montreal, August 2008.
The first mathematical heart model consisted of a single dipole source. It is still used. More recent models couple millions of elements, each represented by a detailed membrane model. We pushed this further by making a bidomain reaction-diffusion model of the human heart with over 50 million elements. In this presentation we discuss how to make such a large bidomain system converge, and what are the useful applications of this large and resource-hungry model.
Computational resources for this work were provided by the Réseau québécois de calcul de haute performance (RQCHP). We gratefully acknowledge financial support from the Research Center of Sacré-Coeur Hospital, Montréal, Québec, Canada; the Interuniversity Cardiology Institute of the Netherlands (ICIN); and The Netherlands Heart Foundation (NHS) grant 2005B092.
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